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AssigneeThe Trustees of Columbia University in the City of New York
InventorsYuan Chang, Roy A. Bohenzky, James J. Russo, Isidore S. Edelman, Patrick S. Moore
Estimating the term…
This invention provides an isolated nucleic acid molecule which encodes KSHV glycoprotein L (gL). This invention provides an isolated nucleic acid molecule which encodes KSHV glycoprotein M (gM). This invention provides isolated gL and gM polypeptides. This invention provides antibodies specific to the polypeptides. Antisense and triplex oligonucleotide molecules are also provided. This invention provides a vaccine for Kaposi's Sarcoma (KS). This invention provides methods of vaccination, prophylaxis, diagnosis and treatment of a subject with KS and of detecting expression of a DNA virus associated with Kaposi's sarcoma in a cell.
An isolated nucleic acid molecule encoding Kaposi's sarcoma-associated herpesvirus glycoprotein M having an amino acid sequence as set forth in SEQ ID NO:2.
An isolated nucleic acid molecule encoding Kaposi's sarcoma-associated herpesvirus glycoprotein L having an amino acid sequence as set forth in SEQ ID NO:23.
Dependencies are inferred from the claim text.