Transport vehicles for macromolecules
AssigneesStitching Voor DeTechnische Wetenschappen, Rijksuniversiteit Groningen, Stichting Scheikundig Ondoerzoek in Nederland
InventorsJan Bernard Frederik Nicolaas Engberts, Anno Wagenaar, Dirk Hoekstra, Irene Van Der Woude, Marcel Herman Jozef Ruiters
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Abstract
The invention relates to new compounds with the general formula I for use as a tool to introduce macromolecules into cells. The invention further relates to compositions for introducing macromolecules into cells, comprising vesicles formed by at least one compound in a solvent. The macromolecule can be incorporated in the vesicles and/or bound to the vesicles or another aggregate of the new compounds. In a preferred embodiment at least one targeting molecule, for instance a (labelled) antibody, may further be attached to the vesicles. ##STR1##
Claims7
A compound with the general formula I ##STR11## in which:
- X is selected from the group consisting of C1.sup.-, Br.sup.- and I.sup.-.
Dependencies are inferred from the claim text.