Pressure distributor and multi-macrocarrier assembly for ballistic transfer transfection apparatus
OwnerBurghardt Wittig, Matthias Schroff +1inventors
InventorsBurghardt Wittig, Matthias Schroff, Joseph Schroff
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Abstract
The ballistic transfer transfection technology employs a cold gas shock wave to accelerate microprojectiles that carry matter into cells by mechanical force. The present invention relates to a device that splits the cold gas shock wave into several individual shock waves that spread the pressure of the initial shock wave to several projectile launching devices. The number of cells transfected by this new device is increased manyfold, compared to the original apparatus. The use of the technology in a clinical context is facilitated.
Claims3
An apparatus for the transfection of cells comprising:
- a) a pressure separation means that divides a cold gas shock wave into more than one pressure wave that propel macroprojectiles into the direction of cells that are to be transfected by biological matter,
- b) a plurality of microprojectile launching devices and
- c) a macroprojectile launching device holding means positioned underneath said pressure separation means, holding in place said plurality of macroprojectile launching devices so as to expose said launching devices to the individual pressure bursts released by said pressure separation means.
Dependencies are inferred from the claim text.