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US 5,852,176 AGranted
Antibodies to receptors for human interleukin-12
AssigneeHoffmann-La Roche Inc.
InventorsUlrich Andreas Gubler, David Howard Presky
Life of this patent
Estimating the term…
Abstract
Antibodies to human IL-12 beta 2 receptor protein or an IL-12 receptor complex, the complex comprising the beta1 receptor protein complexed with a beta2 receptor protein, which complex is capable of binding to human IL-12 with high affinity.
Claims1
An antibody directed against a interleukin-12 (IL-12) beta2 receptor protein which protein
- (a) has low binding affinity for human IL-12, and
- (b) when complexed with a human IL-12 beta1 receptor protein forms a complex having high binding affinity to human IL-12.
Dependencies are inferred from the claim text.