Process for making lactide graft copolymers
AssigneeNational Starch and Chemical Investment Holding Corporation
InventorsJules E. Schoenberg, Robert D. Harlan
Life of this patent
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Abstract
Polylactide or polyglycolide graft copolymers are prepared by a process comprising preparing a backbone polymer from acrylate and/or methacrylate monomers and from one or more polymerizable monomers that contain a functional group unreactive in a free-radical polymerization, the backbone polymer being compatible with lactide monomer or lactide polymer; adding to the resulting polymer up to 40% by total polymer weight, but not 0%, of the D- or L-isomer of lactide in an enantiomeric excess of 84%; heating the mixture of lactide and polymer to a temperature of 80.degree.-175.degree. C. in the presence of a tin catalyst for a period of time effective to polymerize the lactide and react the lactide with the functional group on the backbone polymer.
Claims9
A process for making a graft copolymer, characterized as a thermoplastic elastomeric polymer, having the structure ##STR2## in which X represents the polymer units resulting from the polymerization of one or more monomers (the X monomers) selected from the group consisting of C.sub.2 -C.sub.8 alkyl acrylate, C.sub.2 -C.sub.8 alkyl methacrylate, ethylene and vinyl acetate;
- Y represents the polymer units resulting from the polymerization with the X monomers of a monomer (the Y monomers) selected from the group consisting of 2-hydroxyethyl acrylate, 2-hydroxyethyl methacrylate, hydroxypropyl acrylate, hydroxypropyl methacrylate, allyl alcohol, and N-(t-butyl)aminoethyl methacrylate, the Y monomers present in an amount up to about 6%, but not 0%, by weight of the X monomers;
- Z represents the polymer units resulting from the polymerization of lactide or glycolide, in which the total amount of the lactide or glycolide is present in an amount up to about 40%, but not 0%, by weight of the total polymer weight;
- and
- m and n are integers designating the relative molar amounts of monomer units comprising the backbone chain of the polymer such that the backbone polymer has a number average molecular weight of 10,000-200,000,
- the process comprising:
- (a) preparing a backbone polymer from acrylate and/or methacrylate monomers and from one or more polymerizable monomers that contain a functional group unreactive in a free-radical polymerization, the backbone polymer being compatible with lactide or glycolide monomers or lactide or glycolide polymer;
- (b) adding to the resulting polymer up to 40% by total polymer weight, but not 0%, of glycolide or of the D- or L-isomer of lactide in an enantiomeric excess of 84% or greater;
- (c) heating the mixture of lactide and polymer to a temperature of 80.degree.-175.degree. C. in the presence of a transesterication catalyst for a period of time effective to polymerize the lactide and react the lactide with the functional group on the backbone polymer,
- (d) adding a soluble fluoride salt to the product of step (c) in an amount effective to prevent gellation for at least 24 hours.
Dependencies are inferred from the claim text.