Heteroatom substituted benzoyl derivatives that enhance synaptic response mediated by receptors

A compound having the structure:

• ##STR35## wherein:
• ##STR36## is selected from:
• ##STR37## --Y-- is selected from:
• ##STR38## wherein y is 3, 4, or 5;
• and --(CR.sub.2).sub.x -- and --C.sub.x R.sub.(2x-2) --, wherein x is 4, 5, or 6;
• --R is hydrogen or a straight chain or branched chain alkyl group having 1-6 carbon atoms;
• each --M-- is independently selected from:
• --C(H)-- and
• --C(Z)--, wherein Z is selected from:
• --R and --OR;
• each --Y'-- is independently selected from:
• --O--,
• --Z'-- is selected from:
• --(CR.sub.2).sub.z --, wherein z is 1, 2, or 3, and
• --C.sub.z' R.sub.(2z'-1) --, wherein z' is 1 or 2, or
• --C.sub.2 R.sub.2 --
• with the proviso that:
• if each M is --C(H)--, each Y' is --O-- and Z' is --(CR.sub.2).sub.z --, wherein R is H, methyl or ethyl then Y is not --(CH.sub.2).sub.4,5 --.