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US 5,851,798 AGranted
Nucleic acid encoding human GPR14 receptor
AssigneeSmithKline Beecham Corporation
InventorsUsman Shabon, Derk Bergsma
Life of this patent
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AssigneeSmithKline Beecham Corporation
InventorsUsman Shabon, Derk Bergsma
Estimating the term…
Human GPR14 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing Human GPR14 polypeptides and polynucleotides in the design of protocols for the treatment of infections such as bacterial, fungal, protozoan and viral infections, particularly infections caused by HIV-1 or HIV-2; pain; cancers; anorexia; bulimia; asthma; Parlinson's disease; acute heart failure; hypotension; hypertension; urinary retention; osteoporosis; angina pectoris; myocardial infarction; ulcers; asthma; allergies; benign prostatic hypertrophy; and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, severe mental retardation and dyskinesias, such as Huntington's disease or Gilles dela Tourett's syndrome, among others and diagnostic assays for such conditions.
An isolated polynucteotide comprising a nucleotide sequence encoding the polypeptide having the amino acid sequence set forth in SEQ ID NO:2.
An isolated polynucleotide comprising a nucleotide sequence encoding a naturally occurring human allelic variant of the polypeptide having the amino acid sequence set forth in SEQ ID NO:2.
An expression vector comprising a nucleic acid encoding the polypeptide having the amino acid sequence set forth in SEQ ID NO:2.
An isolated host cell transfected or transformed with the nucleic acid encoding the polypeptide having the amino acid sequence set forth in SEQ ID NO:2.
An expression vector comprising a nucleic acid encoding a naturally occurring human allelic variant of the polypeptide having the amino acid sequence set forth in SEQ ID NO:2.
An isolated host cell transfected or transformed with the nucleic acid encoding a naturally occurring human allelic variant of the polypeptide having the amino acid sequence set forth in SEQ ID NO:2.
Dependencies are inferred from the claim text.