Microtiter plate sealing system
OwnerFrederick R. Blattnerinventor
Life of this patent
Estimating the term…
Abstract
An apparatus for sealing and maintaining a desired temperature of a sample holder includes a non-deformable support, a deformable diaphragm secured to the lower surface of the support and a thermal regulable heater in thermal connection with the diaphragm. The apparatus can be positioned above the upper surface of a sample holder and, upon inflation of the diaphragm, a seal is formed between the diaphragm and the sample holder. When the thermoregulable heating element is activated, the sample holder is maintained at the desired temperature. The temperature can be coordinately regulated with a block heater that heats the underside of the sample holder.
Claims13
An apparatus for sealing and maintaining a desired temperature within at least one well formed into an upper surface of a sample holder, the apparatus comprising:
- a support having a lower surface;
- a deformable diaphragm secured to the lower surface of the support so that the support and the diaphragm define an inflatable chamber therebetween;
- and
- a thermoregulable heating element in thermal connection with the diaphragm,
- wherein when the diaphragm is interposed between the support and the upper surface of the sample holder and the chamber is inflated, a surface of the diaphragm engages the sample holder to form a gas-tight seal between the diaphragm and the at least one well thereby maintaining a desired temperature at the seal.
An apparatus for sealing and maintaining a desired temperature within at least one well formed into an upper surface of a sample holder, the apparatus comprising:
- a support having a lower surface;
- a deformable diaphragm secured to the lower surface of the support, the secured diaphragm and the lower surface of the support defining therebetween an inflatable chamber;
- a gas inlet in fluid communication with the inflatable chamber;
- a thermoregulable thermal heating element in thermal connection with the diaphragm;
- and
- a thermoregulable thermal block heater under coordinated thermal control with the heating element,
- wherein when the diaphragm is interposed between the support and the upper surface of the microtiter dish, and when a gas inflates the inflatable chamber, a surface of the diaphragm engages the sample holder to form a gas-tight seal between the diaphragm and the at least one well thereby maintaining a desired temperature at the seal.
Dependencies are inferred from the claim text.