Module for blood purification, blood purification membrane and its production
AssigneeToyo Boseki Kabushiki Kaisha
InventorsKazuhisa Shibata, Motoki Kyo, Hidehiko Sakurai, Makoto Ohno
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Abstract
A blood purification membrane having a membrane thickness of 10 to 35 .mu.m, an inner diameter of 100 to 300 .mu.m, a porosity of 50 to 85%, a water permeability (ultrafiltration rate) at 37.degree. C. of not less than 20 ml/m.sup.2 .multidot.Hr.multidot.mmHg and a sieving coefficient of albumin of not more than 0.01, a substantially homogeneous interior structure, and a smooth surface structure. A process for producing the membrane and a module are also provided.
Claims11
A blood purification membrane having a membrane thickness of 10 to 35 .mu.m, an inner diameter of 100 to 300 .mu.m, a porosity of 50 to 85%, a water permeability (ultrafiltration rate) at 37.degree. C. of not less than 20 ml/m.sup.2 .multidot.Hr.multidot.mmHg and a sieving coefficient of albumin of not more than 0.01, a substantially homogeneous interior structure, and a smooth surface structure.
A membrane having a membrane thickness of 10 to 35 .mu.m, an inner diameter of 100 to 300 .mu.m, a porosity of 50 to 85%, a water permeability (ultrafiltration rate) at 37.degree. C. of not less than 20 ml/m.sup.2 .multidot.Hr.multidot.mmHg, a sieving coefficient of albumin of not more than 0.01, a substantially homogenous interior structure, a smooth surface structure, and an ultrafiltration rate retention of not less than 80%, said ultrafiltration rate retention being a ratio of a water ultrafiltration rate in hemofiltration at a filtration flow rate of 50 ml/min to a water ultrafiltration rate in hemofiltration at a filtration flow rate of 10 ml/min when the hemofiltration is carried out by flowing bovine blood having a hematocrit value of 30% and a protein concentration of 7 g/dl through a module paced with the membrane at a flow rate of 200 ml/min.
A module packed with a blood purification membrane having a membrane thickness of 10 to 35 .mu.m, an inner diameter of 100 to 300 .mu.m, a porosity of 50 to 85%, a water permeability (ultrafiltration rate) at 37.degree. C. of not less than 20 ml/m.sup.2 .multidot.Hr.multidot.mmHq and a sieving coefficient of albumin of not more than 0.01, a substantially homogeneous interior structure, and a smooth surface structure, in a packing ratio of 40 to 80% and an effective membrane area of 0.9 to 2.5 m.sup.2.
Dependencies are inferred from the claim text.