Process for the preparation of octafluoro-(2,2) paracyclophane
AssigneeSpecialty Coating Systems, Inc.
InventorsWilliam R. Dolbier, Jr., Xiao X. Rong
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Abstract
A process for the preparation of octafluoro-2,2!paracyclophane includes contacting a reactant selected from the group consisting of 1,4-bis(bromodifluoromethyl)benzene (dibromide), 1,4-bis(chlorodifluoromethyl)benzene (dichloride), and 1,4-bis(iododifluoromethyl)benzene (diiodide) with trimethylsilyltributyltin (TMSTBT) (a reducing agent) and fluoride ions in a refluxing solution of hexamethylphosphoramide (HMPA) or dimethylsulfoxide (DMSO) in tetrahydrofuran (THF) at conditions effective to promote a reaction product comprising octafluoro-2,2!paracyclophane.
Claims20
A process for the preparation of octafluoro-paracyclophane which comprises contacting 1,4-bis(bromodifluoromethyl) benzene with a reducing agent and fluoride ions at effective conditions to promote formation of a reaction product comprising octafluoro-paracyclophane.
A method of making a paracyclophane, the method comprising:
- reacting 1,4 bis-(bromodifluoromethyl) benzene with fluoride ions and a reducing agent selected from the group consisting of trimethylsilyltributyltin tributyltin lithium, bis-tributyltin and hexamethyldisilane to form octafluoro-paracyclophane.
Dependencies are inferred from the claim text.