CD40 coding sequences
AssigneeThe General Hospital Corporation
InventorsBrian Seed, Janet Allen, Alejandro Aruffo, David Camerini, Leander Lauffer, Carmen Oquendo, David Simmons, Ivan Stamenkovic, Siegfried Stengelin, Martine Amiot
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Abstract
A simple and highly efficient method for cloning cDNAs from mammalian expression libraries based on transient expression in mammalian host cells has been discovered. The present invention specifically provides the CD40 cDNA sequence.
Claims2
A cloned cDNA encoding a human CD40 cell surface antigen or a functional derivative of said cDNA encoding at least 6 amino acids of human CD40.
Substantially pure cDNA comprising the nucleotide sequence shown in FIG. 16 or a functional derivative of at least 18 nucleotides thereof, wherein said derivative encodes at least 6 amino acids of human CD40.
Dependencies are inferred from the claim text.