.alpha.-subunit of the Mac-1 leukocyte adhesion receptor
AssigneeDana-Farber Cancer Institute, Inc.
InventorsTimothy A. Springer, Angel Corbi
Life of this patent
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Abstract
The present invention relates to Mac-1 alpha-subunit which is involved in the process through which cells recognize and migrate to sites of inflammation as well as attach to cellular substrates during inflammation. The invention is directed toward such molecules, the functional derivatives of such molecules, screening assays for identifying such molecules and therapeutic and diagnostic uses for such molecules.
Claims4
An isolated nucleic acid molecule comprising the nucleic acid sequence depicted in FIG. 2.
An isolated nucleic acid molecule which encodes the amino acid sequence of human MAC-1 alpha-subunit depicted in FIG. 2.
Dependencies are inferred from the claim text.