Balloons for medical catheters

A dilatation catheter balloon formed from a polymeric material comprising:

• about 70 to 79 percent by weight of the total polymeric material composition of a first polymeric component selected from the group consisting of polyesters, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and mixtures thereof, and at least one glycol selected from the group consisting of glycols having the formula HO(CH.sub.2).sub.n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and mixtures thereof;
• about 10 to 20 percent by weight of the total polymeric material composition of a second polymeric component having a Shore hardness less than 75 D, wherein said second polymeric component is a softening ethylene copolymer, and the ethylene copolymer has the formula E'X' or E'X'Y', where E' is ethylene, and is about 60 to 90 percent by weight of the ethylene copolymer, and where X' is about 10 to 40 percent by weight of the ethylene copolymer, and X' is selected from the group consisting of methylacrylate, ethylacrylate, propylacrylate, butylacrylate, and mixtures thereof, and Y', if present, is selected from the group consisting of .alpha., .beta.-ethylenically unsaturated monocarboxylic acids, .alpha., .beta.-ethylenically unsaturated dicarboxylic acids, and anhydrides, and mixtures thereof, comprising from zero to about 15 percent by weight of the ethylene copolymer;
• and
• from zero to about 40 percent by weight of the total polymeric material composition of a compatibilizing ethylene copolymer selected from the group of ethylene copolymers having the formula E/X/Y or E/Y, where
• E is ethylene,
• X is an .alpha., .beta.-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1 to 12 carbon atoms, and
• Y is an .alpha., .beta.-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component, and mixtures thereof, wherein the sum of all the polymeric components is 100 weight percent.

A catheter member formed from a polymeric material, comprising:

• about 60 to 79 percent by weight of the total polymeric material composition of a first polymeric component selected from the group consisting of polyesters and polyamides, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and mixtures thereof, and at least one glycol selected from the group consisting of glycols having the formula HO(CH.sub.2).sub.n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and mixtures thereof, and said polyamides being branched or straight chain polyamides having a molecular weight of at least 5000, and mixtures thereof;
• about 10 to 40 percent by weight of the total polymeric material composition of a second polymeric component having a Shore hardness less than 75 D, wherein said second polymeric component is a softening ethylene copolymer, and the ethylene copolymer is selected from the group consisting of ethylene/butylacrylate/carbon monoxide, ethylene/methylacrylate, ethylene/ethylacrylate, ethylene/butylacrylate, ethylene/vinylacetate, ethylene/methacrylic acid, ethylene/butylacrylate/methacrylic acid, ethylene/methylacrylate/methacrylic acid, ethylene/methylacrylate/maleic anhydride, ethylene/ethyl acrylate/maleic anhydride, and ethylene/butylacrylate/maleic anhydride, and mixtures thereof;
• and
• from zero to about 40 percent by weight of the total polymeric material composition of a compatibilizing ethylene copolymer selected from the group of ethylene copolymers having the formula E/X/Y or E/Y, where
• E is ethylene,
• X is an .alpha., .beta.-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, where the alkyl groups contain 1 to 12 carbon atoms, and mixtures thereof, and
• Y is an .alpha., .beta.-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component, wherein the sum of all the polymeric components is 100 weight percent.

A catheter member formed from a polymeric material, comprising:

• about 60 to 79 percent by weight of the total polymeric material composition of a first polymeric component selected from the group consisting of polyesters and polyamides, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and mixtures thereof, and at least one glycol selected from the group consisting of glycols having the formula HO(CH.sub.2).sub.n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and mixtures thereof, and said polyamides being branched or straight chain polyamides having a molecular weight of at least 5000, and mixtures thereof;
• about 10 to 40 percent by weight of the total polymeric material composition of a second polymeric component having a Shore hardness less than 75 D, wherein said second polymeric component is a softening ethylene copolymer, and said softening ethylene copolymer contains ethylene and at least one other monomer selected from the group consisting of .alpha., .beta.-ethylenically unsaturated monomers, carbon monoxide, and sulfur dioxide, and mixtures thereof, and wherein one of the .alpha., .beta.-ethylenically unsaturated monomers is an acid containing moiety, and the polymer is partially neutralized with an ion selected from the group of sodium, potassium, zinc, magnesium, lithium, calcium, and ammonium, and mixtures thereof;
• and
• from zero to about 40 percent by weight of the total polymeric material composition of a compatibilizing ethylene copolymer selected from the group of ethylene copolymers having the formula E/X/Y or E/Y, where
• E is ethylene,
• X is an .alpha., .beta.-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, where the alkyl groups contain 1 to 12 carbon atoms, and mixtures thereof, and
• Y is an .alpha., .beta.-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component, wherein the sum of all the polymeric components is 100 weight percent.

A catheter member formed from a polymeric material, comprising:

• about 70 to 79 percent by weight of the total polymeric material composition of a first polymeric component selected from the group consisting of polyesters and polyamides, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and mixtures thereof, and at least one glycol selected from the group consisting of glycols having the formula HO(CH.sub.2).sub.n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and mixtures thereof, and said polyamides being branched or straight chain polyamides having a molecular weight of at least 5000, and mixtures thereof;
• about 10 to 20 percent by weight of the total polymeric material composition of a second polymeric component having a Shore hardness less than 75 D, wherein said second polymeric component is a softening ethylene copolymer, and the ethylene copolymer has the formula E'X' or E'X'Y', where E' is ethylene, and is about 60 to 90 percent by weight of the ethylene copolymer, and where X' is about 10 to 40 percent by weight of the ethylene copolymer, and X' is selected from the group consisting of methylacrylate, ethylacrylate, propylacrylate, butylacrylate, and mixtures thereof, and Y', if present, is selected from the group consisting of .alpha., .beta.-ethylenically unsaturated monocarboxylic acids, .alpha., .beta.-ethylenically unsaturated dicarboxylic acids, and anhydrides, and mixtures thereof, comprising from zero to about 15 percent by weight of the ethylene copolymer, and wherein said second polymeric component includes a vinyl silane coupling agent containing a functional group selected from the group consisting of amide, methoxy, epoxide, and anhydride, and combinations thereof, whereby said second polymeric component forms a bond with said first polymeric component, and wherein the sum of all the polymeric components is 100 weight percent.

A dilatation catheter balloon formed from a polymeric material comprising:

• about 60 to 79 percent by weight of the total polymeric material composition of a first polymeric component selected from the group consisting of polyesters, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and mixtures thereof, and at least one glycol selected from the group consisting of glycols having the formula HO(CH.sub.2).sub.n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and mixtures thereof;
• about 10 to 40 percent by weight of the total polymeric material composition of a second polymeric component having a Shore hardness less than 75 D, wherein said second polymeric component is a softening ethylene copolymer, and the ethylene copolymer is selected from the group consisting of ethylene/butylacrylate/carbon monoxide, ethylene/methylacrylate, ethylene/ethylacrylate, ethylene/butylacrylate, ethylene/vinylacetate, ethylene/methacrylic acid, ethylene/butylacrylate/methacrylic acid, ethylene/methylacrylate/methacrylic acid, ethylene/methylacrylate/maleic anhydride, ethylene/ethylacrylate/maleic anhydride, and ethylene/butylacrylate/maleic anhydride, and mixtures thereof;
• and
• from zero to about 40 percent by weight of the total polymeric material composition of a compatibilizing ethylene copolymer selected from the group of ethylene copolymers having the formula E/X/Y or E/Y, where
• E is ethylene,
• X is an .alpha., .beta.-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1 to 12 carbon atoms, and
• Y is an .alpha., .beta.-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component, and mixtures thereof, wherein the sum of all the polymeric components is 100 weight percent.

A dilatation catheter balloon formed from a polymeric material comprising:

• about 70 to 79 percent by weight of the total polymeric material composition of a first polymeric component selected from the group consisting of polyesters, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and mixtures thereof, and at least one glycol selected from the group consisting of glycols having the formula HO(CH.sub.2).sub.n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and mixtures thereof;
• about 10 to 40 percent by weight of the total polymeric material composition of a second polymeric component having a Shore hardness less than 75 D, wherein said second polymeric component is a softening ethylene copolymer, and said softening ethylene copolymer contains ethylene and at least one other monomer selected from the group consisting of .alpha., .beta.-ethylenically unsaturated monomers, carbon monoxide, and sulfur dioxide, and mixtures thereof, and wherein one of the .alpha., .beta.-ethylenically unsaturated monomers is an acid containing moiety, and the polymer is partially neutralized with an ion selected from the group of sodium, potassium, zinc, magnesium, lithium, calcium, and ammonium, and mixtures thereof;
• and
• from zero to about 40 percent by weight of the total polymeric material composition of a compatibilizing ethylene copolymer selected from the group of ethylene copolymers having the formula E/X/Y or E/Y, where
• E is ethylene,
• X is an .alpha., .beta.-ethylenically unsaturated monomer derived from at least one of alkylacrylate, alkylmethacrylate, alkyl vinyl ether, carbon monoxide, sulfur dioxide, or mixtures thereof, where the alkyl groups contain 1 to 12 carbon atoms, and
• Y is an .alpha., .beta.-ethylenically unsaturated monomer containing a reactive group that forms a covalent bond with said first polymeric component, and mixtures thereof, wherein the sum of all the polymeric components is 100 weight percent.

A dilatation catheter balloon formed from a polymeric material comprising:

• about 70 to 79 percent by weight of the total polymeric material composition of a first polymeric component selected from the group consisting of polyesters, said polyesters being prepared from the group of dicarboxylic acids selected from aromatic dicarboxylic acids having from 8 to 14 carbon atoms and aliphatic dicarboxylic acids having from 2 to 12 carbon atoms, and mixtures thereof, and at least one glycol selected from the group consisting of glycols having the formula HO(CH.sub.2).sub.n OH, where n is an integer from 2 to 10, neopentyl glycol and cyclohexane dimethanol, and mixtures thereof;
• about 10 to 20 percent by weight of the total polymeric material composition of a second polymeric component having a Shore hardness less than 75 D, wherein said second polymeric component is a softening ethylene copolymer, and the ethylene copolymer has the formula E'X' or E'X'Y', where E' is ethylene, and is about 60 to 90 percent by weight of the ethylene copolymer, and where X' is about 10 to 40 percent by weight of the ethylene copolymer, and X' is selected from the group consisting of methylacrylate, ethylacrylate, propylacrylate, butylacrylate, and mixtures thereof, and Y', if present, is selected from the group consisting of .alpha., .beta.-ethylenically unsaturated monocarboxylic acids, .alpha., .beta.-ethylenically unsaturated dicarboxylic acids, and anhydrides, and mixtures thereof, comprising from zero to about 15 percent by weight of the ethylene copolymer, wherein said second polymeric component includes a vinyl silane coupling agent containing a functional group selected from the group consisting of amide, methoxy, epoxide, and anhydride, and combinations thereof, whereby said second polymeric component forms a bond with said first polymeric component, and wherein the sum of all the polymeric components is 100 weight percent.