US 5,849,802 A · Fungicidal spirocyclic amines

Abstract

New antimicrobial spirocarbocyclic compounds are described, having the general formula I, ##STR1## or an acid-addition salt thereof, in which R.sub.1 represents an optionally substituted alkyl, cycloalkyl, cycloalkylalkyl, alkoxy, cycloalkoxy, alkoxyalkyl, aralkyl group R.sub.2 and R.sub.3 each independently represent hydrogen or an optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, bicycloalkyl, tricycloalkyl, alkoxyalkyl, aralkyl, aryl or haloaralkyl, a 4- to 6-membered heterocyclyl, tetrahydrofuryl or dioxolanyl group, or R.sub.2 and R.sub.3, together represents an optionally substituted, saturated or unsaturated chain which may optionally contain one or more oxygen atoms and which may optionally be aryl- or cycloalkyl-fused, and n represents zero or an integer from 1 to 3. The invention further relates to the preparation of the above spirocarbocyclic compounds, intermediates prepared during the synthesis of these compounds, compositions containing the compounds and their use as fungicides in the control of phytopathogenic fungi.

Claims16

Dependent claims

A compound of the formula I ##STR14## or an acid-addition salt thereof wherein R.sub.1 represents an optionally substituted C.sub.3-8 alkyl, C.sub.3-6 cycloalkyl, C.sub.3-8 cycloalkyl-C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.1-10 alkoxy-C.sub.1-6 alkyl or phenyl group;

R.sub.2 and R.sub.3 together represent a saturated chain containing four or five carbon atoms optionally interrupted by oxygen atoms and which chain optionally may be aryl- or cyclopentyl fused, wherein each of the above groups is optionally substituted by one or more chlorine or fluorine atoms or C.sub.1-4 alky, C.sub.1-4 haloalkyl, C.sub.4-6 cycloalkenyl or C.sub.1-4 alkoxy groups;
and
n represents zero or an integer from 1 to 3.

A fungicidal composition which comprises at least two carriers, at least one of which is a surface active agent and, as active ingredient, a compound of the general formula I ##STR15## or an acid-addition salt thereof, wherein R.sub.1 represents an optionally substituted C.sub.3-8 alkyl, C.sub.3-6 cycloalkyl, C.sub.3-8 cycloalkyl-C.sub.1-6 alkyl, C.sub.1-6 alkoxy, C.sub.1-10 alkoxy-C.sub.1-6 alkyl or phenyl group;

R.sub.2 and R.sub.3 each independently represent hydrogen or an optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkylalkyl, bicycloalkyl, tricycloalkyl, alkoxyalkyl, aralkyl, aryl or haloaralkyl, a 4- to 6-membered heterocyclyl, tetrahydrofuryl or dioxolanyl group, or R.sub.2 and R.sub.3, together represent an optionally substituted, saturated or unsaturated chain which may optionally contain one or more oxygen, nitrogen or sulphur atoms and which may optionally be aryl- or cycloalkyl-fused;
and
n represents zero or an integer from 1 to 3.

Dependencies are inferred from the claim text.

Fungicidal spirocyclic amines

Life of this patent

Fungicidal spirocyclic amines

Life of this patent

Abstract

Claims16