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US 5,849,800 AGranted
Use of amantadine for treatment of Hepatitis C
AssigneeThe Penn State Research Foundation
InventorJill P. Smith
Life of this patent
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Abstract
Methods for treating patients with viral infection with pharmaceutical agents are disclosed. In one embodiment, the virus is Hepatitis C and the pharmaceutical agent is amantadine. The methods of the present invention can be used in patients that have not responded to or cannot tolerate interferon treatment, as well as patients under the age of eighteen.
Claims21
A method of treating Hepatitis C infection in a human patient, consisting essentially of:
- a) providing:
- i) a patient having symptoms of Hepatitis C infection, and
- ii) a formulation consisting of amantadine;
- and
- b) administering a therapeutically effective dose of said formulation to said patient under conditions such that the symptoms of said infection is reduced.
2 more elements
A method of treating Hepatitis C infection in a human patient, comprising:
- a) providing:
- i) a patient having symptoms of Hepatitis C infection, and
- ii) a formulation comprising amantadine;
- and
- iii) a means for testing alanine aminotransferase levels in said patient;
- b) performing a first test with said means for testing to determine a first alanine aminotransferase level in said patient;
- c) administering a therapeutically effective dose of said formulation to said patient;
- and
- d) performing a second test with said means for testing to determine a second alanine aminotransferase level in said patient, wherein said second level is lower than said first level.
6 more elements
Dependencies are inferred from the claim text.