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AssigneeZaidan Hojin Biseibutsu Kagaku Kenkyu Kai
InventorsShinichi Kondo, Yoko Ikeda, Tomio Takeuchi, Rie Shinei, Shuichi Gomi, Seiji Shibahara, Hiroo Hoshino
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Now are provided (R)-3,6-diamino-N-(.omega.-aminoalkyl)-hexanamides which are novel compounds having the general formula (I): ##STR1## wherein n stands for 2-5, and which may be for example, (R)-3,6-diamino-N-(2-aminoethyl)hexanamide (n=2) and (R)-3,6-diamino-N-(3-aminopropyl)hexanamide (n=3). Their preparation process is also provided. These novel compounds and acid addition salts thereof have activities inhibitory against Gram-positive bacteria, Gram-negative bacteria and AIDS virus, as well as tumor cells and are chemically stable. These novel compounds and their salts are useful as chemotherapeutic agents for diseases caused by these bacteria or virus and also as antitumor agent.
An (R)-3,6-diamino-N-(.omega.-aminoalkyl)hexanamide represented by the general formula (I):
A process for the preparation of an (R)-3,6-diamino-N-(.omega.-aminoalkyl)hexanamide represented by the general formula (I):
A pharmaceutical composition, which comprises as active ingredient an (R) -3,6-diamino-N-(.omega.-aminoalkyl)-hexanamide represented by the general formula (I):
Dependencies are inferred from the claim text.