Treatment of sepsis-induced acute renal failure
AssigneeUniversity of Pittsburgh
InventorsEdwin K. Jackson, Joseph A. Carcillo
Life of this patent
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Abstract
Methods are provided for treating sepsis/endotoxin-induced acute renal failure, and renal vasoconstriction and catecholamine-induced renal and mesenteric vasconstriction by administering to a patient a therapeutically effective amount of a composition comprising at least one drug with Type IV phosphodiesterase inhibiting activity or any combination thereof and a pharmaceutically acceptable carrier.
Claims4
A method for protecting a human subject in need thereof from developing acute renal failure resulting from septicemia/endotoxemia, comprising the step of administering to said subject prior to the onset of septicemia/endotoxemia a therapeutically effective amount of a composition comprising at least one drug with Type IV phosphodiesterase inhibiting activity or any combination thereof and a pharmaceutically acceptable carrier.
A method for protecting a human subject in need thereof from developing acute renal failure or treating acute renal failure in a human subject resulting from septicemia/endotoxemia comprising the step of administering to said subject after the onset of septicemia/endotoxemia a therapeutically effective amount of a composition comprising at least one drug with Type IV phosphodiesterase inhibiting activity or any combination thereof and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.