Use of levobupivacaine as an anesthetic agent
AssigneeDarwin Discovery, Ltd.
InventorsHazel Judith Bardsley, Robert William Gristwood, Andrew John McGlashan Richards
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Abstract
Levobupivacaine ((S)-1-butyl-N-(2,6-dimethylphenyl)-2-piperidinecarboxamide) is useful as an anesthetic, particularly in a patient who is CNS-compromised or predisposed to CNS side-effects. It is also useful as an anesthetic in obstetrics.
Claims20
A method of providing anesthesia, without concomitant adverse systemic side effects, in a patient, comprising administering to the patient levobupivacaine through a route where systemic exposure to said levobupivacaine occurs, wherein said levobupivacaine is present in an enantiomeric excess of at least about 90% with respect to dexbupivacaine.
A method of providing anesthesia in obstetrics, comprising administering to a patient levobupivacaine, wherein said levobupivacaine is present in an enantiomeric excess of at least about 90% with respect to dexbupivacaine.
A method of providing anesthesia, without concomitant adverse systemic side effects, in a patient, comprising administering to the patient levobupivacaine, wherein the route of administration is selected from the group consisting of epidural administration and spinal administration, and wherein said levobupivacaine is present in an enantiomeric excess of at least about 90% with respect to dexbupivacaine.
Dependencies are inferred from the claim text.