Desquamation compositions
AssigneeThe Procter & Gamble Company
InventorDonald L. Bissett
Life of this patent
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Abstract
The subject invention relates to desquamation compositions comprising a combination of salicylic acid and certain zwitterionic surfactants. The subject invention further relates to methods of desquamation in mammalian skin and treating acne in mammalian skin.
Claims18
A method for promoting desquamation of mammalian skin without undesirable side effects, which method comprises topically applying to mammalian skin in need of such treatment a safe and effective amount of a composition comprising:
- a) desquamation actives consisting essentially of:
- (i) a safe and effective amount of salicylic acid;
- and
- (ii) a safe and effective amount of zwitterionic surfactant having the structure:
- ##STR8## wherein R.sup.1 is unsubstituted, saturated or unsaturated, straight or branched chain alkyl having from about 9 to about 22 carbon atoms;
- m is an integer from 1 to 3;
- n is 0 or 1;
- R.sup.2 and R.sup.3 are, independently, alkyl having from 1 to about 3 carbon atoms, unsubstituted or mono-substituted with hydroxy;
- R.sup.4 is saturated or unsaturated, straight or branched chain alkylene, unsubstituted or mono-substituted with hydroxy, having from 1 to about 5 carbon atoms;
- and X is selected from the group consisting of CO.sub.2, SO.sub.3 and SO.sub.4 ;
- and
- b) a topical carrier.
The method of claim 14 wherein R.sup.4 has from 1 to about 3 carbon atoms when X is CO.sub.2, and R.sup.4 has from about 2 to about 4 carbon atoms when X is SO.sub.3.
A method of improving the suppleness and/or smoothness of mammalian skin comprising topically applying to mammalian skin in need of such treatment a safe and effective amount of a composition comprising:
- a) a safe and effective amount of salicylic acid;
- and
- b) a safe and effective amount of zwitterionic surfactant having the structure:
- ##STR9## wherein R.sup.1 is unsubstituted, saturated or unsaturated, straight or branched chain alkyl having from about 9 to about 22 carbon atoms;
- m is an integer from 1 to 3;
- n is 0 or 1;
- R.sup.2 and R.sup.3 are, independently, alkyl having from 1 to about 3 carbon atoms, unsubstituted or mono-substituted with hydroxy;
- R.sup.4 is saturated or unsaturated, straight or branched chain alkylene, unsubstituted or mono-substituted with hydroxy, having from 1 to about 5 carbon atoms;
- and X is selected from the group consisting of CO.sub.2, SO.sub.3 and SO.sub.4.
A method of reducing the appearance of large pores in mammalian skin comprising topically applying to mammalian skin in need of such treatment a safe and effective amount of a composition comprising:
- a) a safe and effective amount of salicylic acid;
- and
- b) a safe and effective amount of zwitterionic surfactant having the structure:
- ##STR10## wherein R.sup.1 is unsubstituted, saturated or unsaturated, straight or branched chain alkyl having from about 9 to about 22 carbon atoms;
- m is an integer from 1 to 3;
- n is 0 or 1;
- R.sup.2 and R.sup.3 are, independently, alkyl having from 1 to about 3 carbon atoms, unsubstituted or mono-substituted with hydroxy;
- R.sup.4 is saturated or unsaturated, straight or branched chain alkylene, unsubstituted or mono-substituted with hydroxy, having from 1 to about 5 carbon atoms;
- and X is selected from the group consisting of CO.sub.2, SO.sub.3 and SO.sub.4.
Dependencies are inferred from the claim text.