Sulfated polysaccharides obtained from heparin, preparation process, pharmaceutical composition and use thereof
AssigneeRhone-Poulenc Rorer S.A.
InventorAndre Uzan
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Abstract
This invention relates to mixtures of sulfated oligosaccharides which possess antithrombotic properties and are useful for the treatment and prevention of venous and arterial thrombosis, prevention of arterial thrombotic accidents, and in the prevention of thrombosis in surgical equipment, to pharmaceutical compositions including such mixtures, to processes for preparing such mixtures, and to the use of such mixtures in the prevention of thrombosis in surgical equipment.
Claims14
A mixture of sulphated oligosaccharides obtained from native or depolymerized heparin comprising at least 70% of oligosaccharides having a molecular weight between 5,400 and 7,800 daltons, at least 5% of oligosaccharides having a molecular weight greater that 6,900 daltons, and having an anti-IIa activity greater than approximately 60 IU/mg.
Dependencies are inferred from the claim text.