Microbiological process for producing .gamma.-decalactone
AssigneeGivaudan Roure (International) SA
InventorsBruno Kumin, Thomas Munch
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Abstract
A microbiological process for the production of .gamma.-decalactone. According to this process, a culture of the fungus of a particular species of the genus Mucor is incubated with the particular substrate, which is an organic carboxylic acid ester, to produce fermentatively the .gamma.-decalactone. Exact conditions have now been discovered under which .gamma.-decalactone can be prepared in high yields. These conditions are based upon the fermentative incubation of a fungus of the genus Mucor in conjunction with the appropriate substrate in order to obtain the high yield of the desired lactone.
Claims5
A microbiological process for the production of .gamma.-decalactone, which comprises:
- a) incubating first in a nutrient broth a culture of a fungus of the species Mucor circinelloides,
- b) forcing a primary reaction product by adding the substrate ethyl decanoate, wherein this substrate is continuously added at a feed rate of from about 2 g to about 3 g per hour per liter of nutrient broth, leading to a substrate concentration in the nutrient broth being from about 0.1% to about 1.5% by weight, relative to the total weight of the nutrient broth, and
- c) then lactonizing the primary reaction product which is formed in step (b).
Dependencies are inferred from the claim text.