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AssigneeGenelabs Technologies, Inc.
InventorsJungsuh P. Kim, Kirk E. Fry, LaVonne Marie Young, Jeffrey M. Linnen, John Wages
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Polypeptide antigens are disclosed which are immunoreactive with sera from individuals having a non-A, non-B, non-C, non-D, non-E Hepatitis, herein designated Hepatitis G Virus (HGV). Corresponding genomic-fragment clones containing polynucleotides encoding the open reading frame sequences for the antigenic polypeptides are taught. The antigens are useful in diagnostic methods for detecting the presence of HGV in test subjects. The antigens are also useful in vaccine and antibody preparations. In addition, the entire coding sequences of two HGV isolates are disclosed. Methods are presented for nucleic acid-based detection of HGV in samples and also methods for the isolation of further genomic sequences corresponding to HGV.
A vector comprising a Non-A Non-B Non-C Non-D Non-E Hepatitis Virus (HGV) polynucleotide composed of a contiguous series of nucleotides contained in SEQ ID NO:14 operably linked to a control sequence, where said polynucleotide encodes a product at least 10 amino acids in length,
Dependencies are inferred from the claim text.