Diagnosis of preeclampsia in mammals
OwnerCamilla M. Olson, Charles Petersoninventors
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Abstract
An improved method of diagnosing preeclampsia comprising the steps of a. collecting blood from a pregnant female mammal; and b. detecting in said blood significantly elevated levels of at least one substance selected from the group consisting of: (1) a hemoglobin variant or hemoglobin variant precursor and (2) a red blood cell glycolytic enzyme or a red blood cell glycolytic enzyme precursor. By detecting the presence of an appropriate "marker" in the blood, preeclampsia can be diagnosed at an earlier stage, thus making possible timely therapeutic intervention. An assay kit for detecting the markers is also provided.
Claims13
A method for the diagnosis of preeclampsia comprising the steps of:
- (a) collecting blood from a pregnant female mammal;
- and
- (b) detecting in said blood significantly elevated levels of at least one substance selected from the group consisting of:
- (1) a hemoglobin variant or hemoglobin variant precursor and
- (2) a red blood cell glycolytic enzyme or a red blood cell glycolytic enzyme precursor.
An assay kit for the diagnosis of preeclampsia comprising a means for detecting in the blood of a pregnant female mammal significantly elevated levels of at least one substance selected from the group consisting of:
- (a) a hemoglobin variant or hemoglobin variant precursor and
- (b) a blood cell glycolytic enzyme or a red blood cell glycolytic enzyme precursor.
An assay kit for diagnosing preeclampsia comprising reagents for assaying significantly elevated levels of at least one substance selected from the group consisting of:
- a. a hemoglobin variant or hemoglobin variant precursor and
- b. a red blood cell glycolytic enzyme or a red blood cell glycolytic enzyme precursor.
Dependencies are inferred from the claim text.