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US 5,849,247 AGranted
Automatic apparatus for immunological assay
AssigneeMerck & Co., Inc.
InventorsMichel Uzan, Thierry Gicquel
Life of this patent
Estimating the term…
Abstract
Automatic immunological assay apparatus comprising reaction wells in which there are deposited quantities of samples to be analyzed and of reagents, the reaction wells being grouped in modules (40) that are moved in translation, sliding between rails that define a U-shaped track (24), running from automatic reaction well feed device (26) to device (28) for ejecting the wells after use.
Claims16
Automatic immunological assay apparatus, comprising:
- (a) at least one module comprising a plurality of longitudinally juxtaposed reaction wells;
- (b) means for providing at least one sample to be analyzed;
- (c) means for providing at least one magnetic bead reagent;
- (d) means for introducing determined quantities of sample and reagent into a reaction well;
- (e) means for reading assay results;
- (f) an open loop track comprising fixed elements, which track supports and guides the modules;
- (g) a chain or belt that extends along the track and engages the modules to move the modules from an upstream end of the track to a downstream end of the track;
- (h) automatic module feed means and module ejection means being provided respectively at the upstream end and at the downstream end of said track;
- (i) means for moving the reaction wells stepwise in a downstream direction past the means for introducing sample and reagent and the means for reading the results;
- and
- (j) two magnetic bead washing heads respectively disposed at separate positions on opposite branches of the track for washing magnetic beads contained in reaction wells of a module positioned under the respective washing head, with both washing heads being movable between a first, rest position, and a second, working position, and being carried by a common support for vertical displacement between the two positions,
- wherein the means for reading assay results comprises two systems for optically reading assay results, said systems being spaced apart from each other on the track with a first of the two systems being adapted for reading the results of single-reagent type assays and a second of the two systems being adapted for reading the results of dual-reagent type assays.
9 more elements
Dependencies are inferred from the claim text.