Process for the preparation of nootkatone
AssigneeFirmenich SA
InventorsBernard Muller, Christopher Dean, Christian Schmidt, Jean-Charles Kuhn
Life of this patent
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Abstract
A method for preparing nootkatone, nootkatol or mixtures thereof by oxidizing valencene, wherein the valencene is exposed to an oxygenated atmosphere in a suitable reaction medium and in the presence of an unsaturated fatty acid hydroperoxide, and the nootkatone and/or nootkatol is (are) optionally separated from the reaction medium. The method enables nootkatone yields of around 60 g per kg of reaction medium to be achieved.
Claims17
Process for the preparation of nootkatone or nootkatol, or of mixtures of these compounds, by oxidation of valencene, characterized in that the latter is exposed to an oxygen-containing atmosphere in an appropriate reaction medium and in the presence of a hydroperoxyde of an unsaturated fatty acid and in that, optionally, the nootkatone and/or the nootkatol is separated from the reaction mixture.
Process for the preparation of nootkatone or nootkatol, or of mixtures of these compounds, by oxidation of valencene, characterized in that valencene is exposed to an oxygen-containing atmosphere in an appropriate reaction medium and in the presence of a hydroperoxide of an unsaturated fatty acid, wherein the nootkatone and/or the nootkatol is optionally separated from the reaction mixture, and said hydroperoxide is formed in situ in the reaction medium from the unsaturated fatty acid.
Process for the preparation of nootkatone or nootkatol, or of mixtures of these compounds, by oxidation of valencene, characterized in that the valencene is exposed to an oxygen-containing atmosphere in an appropriate reaction medium and in the presence of a hydroperoxide of an unsaturated fatty acid, with the nootkatone and/or the nootkatol is optionally separated from the reaction mixture, the valencene is used in the form of one of its optically active isomers, and the corresponding optically active isomer of nootkatone and/or nootkatol is obtained.
Dependencies are inferred from the claim text.