Labelled compound
OwnerYasuyoshi Watanabe, Hironori Omura +3inventors
InventorsYasuyoshi Watanabe, Hironori Omura, Yuji Furuya, Bengt Langstrom, Gunnar Antoni
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Abstract
The present invention provides a labelled .beta.-cyano-L-alanine and a .gamma.-cyano-.alpha.-aminobutyric acid, of which cyano group carbon is labelled with radionuclide .sup.11 C or .sup.14 C, or stable isotope .sup.13 C. The present invention also provides a labelled amino acids such as asparagine, asparatic acid, DABA, GABA, glutamine and glutamic acid synthesized by using the labelled .beta.-cyano-L-alanine and the .gamma.-cyano-.alpha.-aminobutyric acid as an intermediate. The labelled amino acids are useful for in vivo imaging of tumors and brain functions.
Claims1
A labelled compound, which is .beta.-cyano-L-alanine, a salt thereof or a derivative thereof having protecting group, of which cyano group carbon is labelled with positron nuclide .sup.11 C.
Dependencies are inferred from the claim text.