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US 5,847,108 AGranted
Clathrate of isoflavone derivatives and edible composition comprising the same
AssigneeFujicco Co., Ltd.
InventorsSatomi Kanaoka, Takehiko Uesugi, Kuniaki Hirai, Toshiya Toda, Takenori Okuhira
Life of this patent
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Abstract
Clathrate compounds comprising an isoflavone derivative and a cyclodextrin are disclosed. The clathrate compounds have improved water solubility and good taste properties, thereby making the compounds a useful ingredient in edible compositions.
Claims3
A clathrated compound comprising:
- (a) an isoflavone derivative selected from the group consisting of daidzein, genistein, glycitein, genistin, glycitin, 6"-O-malonyldaidzin, 6"-O-malonylgenistin, 6"-O-malonylglycitin, 6"-O-acetyldaidzin, 6"-O-acetylgenistin, 6"-O-acetylglycitin, 6"-O-succinyldaidzin, 6"-O-succinylgenistin, 6"-O-succinylglycitin, and mixtures thereof, and
- (b) a cyclodextrin selected from the group consisting of a .beta.-cyclodextrin, a .gamma.-cyclodextrin, and mixtures thereof,
- wherein the compound has less bitterness, astringency, and roughness than a corresponding nonclathrated isoflavone derivative when orally administered.
A clathrated compound comprising:
- (a) an isoflavone derivative selected from the group consisting of daidzein, genistein, glycitein, genistin, glycitin, 6"-O-malonyldaidzin, 6"-O-malonylgenistin, 6"-malonylglycitin, 6"-O-acetyldaidzin, 6"-O-acetylgenistin, 6"-O-acetylglycitin, 6"-O-succinyldaidzin, 6"-O-succinylgenistin, 6"-O-succinylglycitin, and mixtures thereof;
- and
- (b) a cyclodextrin selected from the group consisting of .beta.-cyclodextrin, a .gamma.-cyclodextrin, and mixtures thereof,
- wherein the compound is prepared by clathrating the cyclodextrin and the isoflavone derivative in a weight ratio of cyclodextrin to isoflavone derivative of 0.1:1 to 50:1, and
- wherein the compound has less bitterness, astringency, and roughness than a corresponding nonclathrated isoflavone derivative when orally administered .
2 more elements
Dependencies are inferred from the claim text.