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US 5,847,093 AGranted
Human apoptosis regulator
AssigneeIncyte Pharmaceuticals, Inc.
InventorsOlga Bandman, Surya K. Goli, Jennifer L. Hillman
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AssigneeIncyte Pharmaceuticals, Inc.
InventorsOlga Bandman, Surya K. Goli, Jennifer L. Hillman
Estimating the term…
The present invention provides a human apoptosis regulator protein (APRG) and polynucleotides which identify and encode APRG. The invention also provides genetically engineered expression vectors and host cells comprising the nucleic acid sequences encoding APRG and a method for producing APRG. The invention also provides for agonists, antibodies, or antagonists specifically binding APRG, and their use, in the prevention and treatment of diseases associated with expression of APRG. Additionally, the invention provides for the use of antisense molecules to polynucleotides encoding APRG for the treatment of diseases associated with the expression of APRG. The invention also provides diagnostic assays which utilize the polynucleotide, or fragments or the complement thereof, and antibodies specifically binding APRG.
An isolated and purified polynucleotide sequence encoding a polypeptide having the amino acid sequence of SEQ ID NO:1.
An isolated and purified polynucleotide sequence consisting of SEQ ID NO:2.
Dependencies are inferred from the claim text.