Process for obtaining platelet factor-4
AssigneeJCR Pharmaceuticals Co., Ltd.
InventorsYoshikazu Komurasaki, Chihiro Shindoh, Takashi Hirose, Keihide Koh, Satoshi Nishimuro
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Abstract
The present invention, using a readily available sulfated chitin as an adsorbent, can permit platelet factor-4 to be recovered through specific adsorption from a solution containing the same factor, in by far increased yields as compared with the conventional process utilizing a heparin-immobilized affinity column, and provides the process for isolating, through purification platelet factor-4 which is suited for a commercial-scale, mass production process, wherein there can be offered the advantages of utilization of more readily available sulfated chitin, simplified procedure and improved production yields for the objective substance.
Claims6
A process for isolating platelet factor-4, which comprises contacting a solution containing platelet factor-4 with a sulfated chitin to adsorb the said factor, followed by elution of the said factor from the adsorption body.
Dependencies are inferred from the claim text.