Benzamidoxime derivatives, process production thereof, and agrohorticultural bactericide
AssigneeNippon Soda Co., Ltd.
InventorsIsamu Kasahara, Hirohito Ooka, Shinsuke Sano, Hiroyasu Hosokawa, Homare Yamanaka
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AssigneeNippon Soda Co., Ltd.
InventorsIsamu Kasahara, Hirohito Ooka, Shinsuke Sano, Hiroyasu Hosokawa, Homare Yamanaka
Estimating the term…
The present invention relates to benzamidoxime derivatives represented by the formula I!; ##STR1## wherein R.sup.1 is unsubstituted or substituted C.sub.1 -C.sub.4 alkyl, unsubstituted or substituted C.sub.2 -C.sub.4 alkenyl or unsubstituted or substituted C.sub.2 -C.sub.4 alkynyl, R.sup.2 is phenyl optionally having substituents or heterocycle optionally having substituents, X.sup.1, X.sup.2, X.sup.3 and X.sup.4 are each independently hydrogen, halogen, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 haloalkyl, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 haloalkoxy, C.sub.1 -C.sub.4 alkylthio or the like, and r.sub.1 and r.sub.2 are each independently hydrogen, C.sub.1 -C.sub.4 alkyl or the like, having excellent fungicidal activity and being useful as a fungicide for agricultural and horticultural use, and methods for preparation thereof.
Benzamidoxime derivatives represented by the formula I!:
Benzamidoxime derivatives represented by the formula I'!:
Benzamidoxime derivatives represented by the formula (I'):
Dependencies are inferred from the claim text.
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Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to…:…
Five-membered rings: with sulfur as the ring hetero atom
Having rings with two nitrogen atoms as the only ring hetero atoms: 1,2-Diazoles; Hydrogenated 1,2-diazoles
With replacement of the other oxygen atom of the carboxyl group by nitrogen atoms, e.g. N-hydroxyamidines: having carbon atoms of hydroxamidine…
Term ended 14 Aug 2017 (estimated)
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This application is a 371 of PCT/JP95/02596 filed Dec. 18, 1995.
The present invention relates to novel benzamidoxime derivatives, methods for preparation thereof and fungicides for agricultural and horticultural uses.
In farming of agricultural and horticultural crops in the past, various fungicides have been used for the control of plant diseases on the crops, however, many of them are not enough useful because of their insufficient effectiveness in plant disease control, the limitation in their use due to the appearance of resistant strain of plant disease pathogens to the fungicides, the development of phytotoxicity and contamination to the crops, and/or their strong toxicity to humans, domestic animals and wildlife. For this reason, there is still intensive requirement to develop safe fungicides for agricultural and horticultural uses, which do not have the disadvantages as described above.
Now, the present invention is further described in detail with referring to the examples described hereinbelow.
Preparation of N'-cyclopropylmethyloxy-N-(4-methoxyphenyl)acetyl-2-fluoro-6-trifluorometh ylbenzamidine(Compound No. 56) ##STR5##
In 200 ml of benzene was dissolved 20.0 g of N'-cyclopropylmethyloxy-2-fluoro-6-trifluoromethylbenzamidine, and to the solution was added 16. 0 g of 4-methoxyphenylacetylchloride. The solution was heated under refluxing for 10 hours. After cooling, ethyl acetate was added to the solution, followed by washing with water and drying over anhydrous magnesium sulfate. The organic layer was concentrated under reduced pressure and the residue was subjected to silica gel column chromatography to obtain 23.6 g of the objective compound.m.p. 75.degree.-76.degree. C.