Oxa acids and related compounds for treating skin conditions
AssigneeAvon Products, Inc.
InventorsDmitri Ptchelintsev, Neil Scancarella, Robert Kalafsky
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Abstract
Described are the use of compounds of Formula (I) depicted below, as active principals for treating skin conditions and compositions containing these compounds, ##STR1## where R.sub.4 is (CR.sub.5 R.sub.6 --CR.sub.7 R.sub.8 --X.sub.1).sub.n --CR.sub.9 R.sub.10 R.sub.11 ; n is an integer from 1 to 18; R.sub.1, R.sub.2, R.sub.3, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9, R.sub.10 and R.sub.11 are, independently, hydrogen or substituents selected from alkyls, alkenyls, oxa-alkyls, aralkyls and aryls; and X, X.sub.1, Y and Z are, independently, oxygen.
Claims24
A topical composition comprising a topical vehicle and a compound of Formula (I):
- ##STR4## wherein, R.sub.4 is (CR.sub.5 R.sub.6 --CR.sub.7 R.sub.8 --X.sub.1).sub.n --CR.sub.9 R.sub.10 R.sub.11 ;
- n is an integer from 1 to 18;
- R.sub.1, R.sub.2, R.sub.3, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9, R.sub.10, and R.sub.11 are, independently, hydrogen or substituents selected from the group consisting of alkyls, alkenyls, oxa-alkyls, aralkyls, aryls, cycloalkyls and cycloalkenyls;
- and X, X.sub.1, Y and Z are O.
A method of treating skin conditions caused by, accompanied with or exacerbated by abnormal desquamation, comprising applying to said skin conditions an effective amount of a compound of Formula (I):
- ##STR5## wherein, R.sub.4 is (CR.sub.5 R.sub.6 --CR.sub.7 R.sub.8 --X.sub.1).sub.n --CR.sub.9 R.sub.10 R.sub.11 ;
- n is an integer from 1 to 18;
- R.sub.1, R.sub.2, R.sub.3, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9, R.sub.10, and R.sub.11, are, independently, hydrogen or substituents selected from the group consisting of alkyls, alkenyls, oxa-alkyls, aralkyls, aryls, cycloalkyls and cycloalkenyls;
- and X, X.sub.1, Y and Z are O.
Dependencies are inferred from the claim text.