Pyrazole derivatives

Pyrazole compounds of the following general formula (1), and their tautomers and salts:

• ##STR90## wherein R.sup.1 represents a hydrogen atom, a C.sub.1 -C.sub.10 alkyl group (said alkyl group is unsubstituted or substituted by one or more substituents selected from a halogen atom, a hydroxyl group and a C.sub.1 -C.sub.10 alkoxy group), a C.sub.2 -C.sub.10 alkenyl group (said alkenyl group is unsubstituted or substituted by one or more substituents selected from a halogen atom, a hydroxyl group and a C.sub.1 -C.sub.10 alkoxy group), a C.sub.2 -C.sub.10 alkynyl group (said alkynyl group is unsubstituted or substituted by one or more substituents selected from a halogen atom, a hydroxyl group and a C.sub.1 -C.sub.10 alkoxy group), a C.sub.3 -C.sub.10 cycloalkyl group (said cycloalkyl group is unsubstituted or substituted by one or more substituents selected from a halogen atom, a hydroxyl group and a C.sub.1 -C.sub.10 alkoxy group), a C.sub.3 -C.sub.10 cycloalkenyl group (said cycloalkenyl group is unsubstituted or substituted by one or more substituents selected from a halogen atom, a hydroxyl group and a C.sub.1 -C.sub.10 alkoxy group) or a C.sub.6 -C.sub.10 aromatic group (said aromatic group is unsubstituted or substituted by one or more substituents selected from a C.sub.1 -C.sub.10 alkyl group, a halogen atom, a hydroxyl group and a C.sub.1 -C.sub.10 alkoxy group);
• R.sup.2 represents COX.sup.1 R.sup.12, wherein R.sup.12 represents a hydrogen atom or a C.sub.1 -C.sub.10 alkyl group and X.sup.1 represents an oxygen atom or a sulfur atom;
• R.sup.3 represents a heterocyclic group {said heterocyclic group represents a thienyl group, pyridyl group or pyrimidinyl group (these groups are unsubstituted or substituted by one or more substituents selected from a C.sub.1 -C.sub.10 alkyl group and a halogen atom)};
• R.sup.4, R.sup.5 and R.sup.6 each independently represents a hydrogen atom, a halogen atom, a hydroxyl group or a C.sub.1 -C.sub.10 alkyl group;
• R.sup.7 represents a 5-tetrazolyl group,
• X represents a nitrogen atom,
• Y and Z each independently represent CR.sup.40, wherein R.sup.40 represents a hydrogen atom, a halogen atom or a C.sub.1 -C.sub.10 alkyl group;
• A represents (CR.sup.41 R.sup.41')m.sup.7, wherein m.sup.7 represents 0, 1, 2 or 3, and R.sup.41 and R.sup.41' each independently represents a hydrogen atom or a C.sub.1 -C.sub.10 alkyl group;
• D represents a C.sub.6 -C.sub.10 aromatic group, wherein said aromatic group is unsubstituted or mono-substituted to penta-substituted by a halogen atom or a C.sub.1 -C.sub.10 alkyl group;
• E represents CR.sup.52 R.sup.53, wherein R.sup.52 and R.sup.53 each independently represents a hydrogen atom or a C.sub.1 -C.sub.10 alkyl group;
• and
• G represents a covalent bond.