Rapid ophthalmic disinfection solution using salt and glycol and/or lower alkanol and surfactant
AssigneeCIBA Vision Corporation
InventorsFu-Pao Tsao, Susan Ann Littlefield, John Harlan Stone
Life of this patent
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Abstract
A disinfection solution, primarily for use in conjunction with contact lenses is disclosed comprising an amount of a pharmaceutically acceptable ionic salt which is equivalent in ionic strength to at least 5% w/v sodium chloride, at least one of a C.sub.2-6 alkanol and a C.sub.3-8 alkylene glycol, a pharmaceutically acceptable surfactant, optionally a buffer, and water.
Claims12
A contact lens polymeric material cleaning and disinfecting solution, comprising:
- (a) x percent by weight of a C.sub.3 -C.sub.8 alkylene glycol and y percent of a C.sub.2 -C.sub.6 alkanol, wherein x and y are each independently 0 to 50 and satisfy the equation (x/10 +y/2>1.0);
- (b) an amount of about 2 weight percent to about 15 weight percent of an ophthalmic device material-compatible surfactant;
- (c) an amount up to about 2 weight percent of a pH adjusting or regulating agent;
- (d) an amount of tonicity builder sufficient to raise the solution tonicity to at least the equivalent of a 5 weight percent or more sodium chloride solution;
- (e) an amount of viscosity-enhancing agent;
- and
- (f) an ophthalmologically acceptable solvent, wherein said composition is capable of simultaneously disinfecting and cleaning said contact lens polymeric material when contacted for a period less than about 60 seconds.
A composition for simultaneously cleaning and disinfecting contact lenses, comprising:
- (a) 5 to 20 weight percent sodium chloride;
- (b) 2 to 15 weight percent surfactant;
- (c) x to 50 weight percent of an alkylene glycol having between 3 and 8 carbon atoms;
- (d) y to 30 weight percent of a lower alkanol having 2 to 6 carbon atoms, wherein x and y are defined by the equation x/10+y/2.gtoreq.1.0;
- (e) 0 to 2 weight percent pH regulating agent;
- (f) a viscosity enhancing agent;
- and
- (g) an ophthalmologically acceptable solvent;
- wherein said composition has a pH of 5 to 7, and wherein said composition is capable of disinfecting and cleaning a contact lens when applied by rubbing said composition with said lens over a period of less than about 60 seconds.
A composition for simultaneously cleaning and disinfecting contact lenses, consisting essentially of:
- (a) about 5 to about 20 weight percent sodium chloride;
- (b) about 2 to about 15 weight percent surfactant;
- (c) about x to about 50 weight percent of an alkylene glycol having between 3 and 8 carbon atoms;
- (d) about y to about 30 weight percent of a lower alkanol having 2 to 6 carbon atoms, wherein x and y are defined by the equation x/10+y/2.gtoreq.1.0;
- (e) 0 to about 2 weight percent pH regulating agent;
- (f) a viscosity enhancing agent;
- and
- (g) an ophthalmologically acceptable solvent;
- wherein said composition is capable of disinfecting and cleaning a contact lens when applied by rubbing said composition for a period less than about 60 seconds.
Dependencies are inferred from the claim text.