Motif Libraries
AssigneeSelectide Corporation
InventorsNikolai Sepetov, Victor Krchnak, Michal Lebl
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AssigneeSelectide Corporation
InventorsNikolai Sepetov, Victor Krchnak, Michal Lebl
Estimating the term…
The invention concerns libraries of chemical compounds, that are useful in medicinal chemistry and related arts, their methods of manufacture and methods of their use. In one embodiment the individual chemical species of the library are synthesized aleatoricly, i.e, by a process involving chance. The chemical species of the library are used while attached to solid phase supports. The library differs from previously disclosed libraries that were intended to be screened while in solid phase in that each individual solid phase support or identifiable portion of a solid phase array displays many species of ligands, collectively termed a "set." The library is constructed so that each set contains a single invariant structure, common to all the species of ligands attached to the particular solid phase support, which is termed a "motif." The invention teaches that libraries of motifs can be employed advantageously compared to known libraries wherein a single species is present on each support.
A library consisting of a multiplicity of sets, each said set comprising a multiplicity of species of test ligands, in which:
Dependencies are inferred from the claim text.