Feline derived T-cell lines for producing FIV
AssigneesUniversity of Florida, University of California
InventorJanet K. Yamamoto
Life of this patent
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Abstract
The subject invention pertains to novel methods and compositions for protecting cats from infection by a broad range of FIV strains using a multi-subtype FIV vaccine. Multi-subtype FIV vaccines comprising either cell free whole virus or cell lines infected with viruses are described. Methods for vaccinating cats with the subject vaccine compositions are also described. Cats vaccinated according to the methods and compositions of the subject invention exhibit protective humoral and cellular immune responses to FIV when challenged with homologous or heterologous strains of FIV. The subject invention also pertains to novel feline cell lines that are susceptible to infection by FIV and their methods of use.
Claims6
A feline-derived T cell line designated as FeT-1C and having ATCC accession number CRL 11968.
A feline-derived T cell line designated as FeT-J and having ATCC accession number CRL11967.
A feline derived T cell line designated as Shi/FeT-1C and having ATCC accession number CRL 11976, wherein said cell line is infected with FIV virus strain FIV.sub.Shi.
A feline derived T cell line designated as Bang/FeT-J and having ATCC accession number CRL 11975, wherein said cell line is infected with FIV virus strain FIV.sub.Bang.
Dependencies are inferred from the claim text.