Culture of swine infertility and respiratory syndrome virus in simian cells
AssigneesBoehringer Ingelheim Animal Health, Inc., South Dakota State University, Regents of the University of Minnesota
InventorsJames E. Collins, David A. Benfield, Danny W. Chladek, Louis L. Harris, David E. Gorcyca
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Abstract
The invention includes a vaccine and sera for treatment of Mystery Swine Disease (MSD), a method for producing the vaccine, methods for diagnosis of MSD, a viral agent that will mimic "mystery swine disease" and antibodies to the viral agent useful in diagnosis and treatment of MSD. The serum contains mammalian antibodies which are effective in treating MSD.
Claims18
A culture of a fastidious, non-hemagglutinating, enveloped RNA virus, wherein the virus is swine infertility and respiratory syndrome virus ATCC VR-2332.
A composition comprising swine infertility and respiratory syndrome virus in a culture of simian organ cells, wherein the swine infertility and respiratory syndrome virus is a fastidious, non-hemagglutinating, enveloped RNA virus and is capable of effecting swine infertility and respiratory syndrome in swine.
A composition comprising attenuated swine infertility and respiratory syndrome virus in a culture of simian cells, wherein the attenuated swine infertility and respiratory syndrome virus is produced by a process comprising passaging a swine infertility and respiratory syndrome virus through simian cells, said swine infertility and respiratory syndrome virus being a fastidious, non-hemagglutinating, enveloped RNA virus.
Dependencies are inferred from the claim text.