Nucleic acids encoding murine UCP3 genes
AssigneeTularik Inc.
InventorsNing Zhang, M. Catherine Amaral, Jin-Long Chen
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Abstract
The invention provides methods and compositions relating to a novel family of genes, mUCP3s, involved in metabolic regulation. The polypeptides may be produced recombinantly from transformed host cells from the disclosed mUCP3 encoding nucleic acids or purified from mammalian cells. The invention provides isolated mUCP3 hybridization probes, knock-out/in constructs and primers capable of specifically hybridizing with the disclosed mUCP3 genes, mUCP3-specific binding agents such as specific antibodies, animals and cells modified with the subject mUCP3 nucleic acids, and methods of making and using the subject compositions in the biopharmaceutical industry.
Claims20
An isolated or recombinant nucleic acid encoding a polypeptide comprising the amino acid sequence set forth as SEQ ID NO:
- 2, 4 or 6.
An isolated or recombinant nucleic acid comprising an entire strand of the nucleic acid sequence set forth as SEQ ID NO:
- 1, 3 or 5.
Dependencies are inferred from the claim text.