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US 5,846,735 AGranted
Hepatitis C virus Fc-binding function
AssigneeUniversity of Iowa Research Foundation
InventorsJack T. Stapleton, Jian-Qiu Han, Douglas LaBrecque, Warren N. Schmidt
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Abstract
The present invention involves the detection and purification of Hepatitis C Virus (HCV). More particularly, the invention involves the exploitation of a newly discovered Fc-binding function in HCV to capture HCV from infected samples. This permits greatly simplified methods of diagnosis, improved methods of treatment and, in addition, the first opportunity to purify significant quantities of HCV.
Claims20
A method of detecting HCV in a sample comprising the steps of:
- (a) obtaining said sample from an individual;
- (b) contacting said sample with Fc-containing polypeptide, said polypeptide lacking antigen binding specificity for HCV;
- and
- (c) detecting HCV bound to the Fc portion of said Fc-containing polypeptide.
1 more element
Dependencies are inferred from the claim text.