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US 5,846,712 AGranted
Tumor suppressor gene, HIC-1
AssigneeThe Johns Hopkins University School of Medicine
InventorsStephen B. Baylin, Michele Makos Wales
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Abstract
Polynucleotide and polypeptide sequences encoding a novel tumor suppressor, HIC-1, are provided. Also included is a method for detecting a cell proliferative disorder associated with HIC-1. HIC-1 is a marker which can be used diagnostically, prognostically and therapeutically over the course of such disorders.
Claims13
A method for detecting a cell proliferative disorder associated with HIC-1 nucleic acid in a subject, comprising contacting a target cellular component containing HIC-1 nucleic acid with a reagent which reacts with HIC-1 nucleic acid and detecting HIC-I nucleic acid.
Dependencies are inferred from the claim text.