Method for imaging mammalian tissue using 1-substituted-1,4,7-tricarboxymethyl-1,4,7,10-tetraazacyclododecane and analogs
AssigneeBracco Diagnostics Inc.
InventorsMichael F. Tweedle, Glen T. Gaughan, James J. Hagan
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Abstract
A method for imaging mammalian tissue utilizing a non-ionic complex of a paramagnetic ion of lanthanide element and a macrocyclic chelating agent.
Claims19
A complex for imaging mammalian tissue, comprising a paramagnetic ion and a tetraazacyclo compound, the complex being charge neutral in aqueous solution.
A complex used for imaging mammalian tissue, comprising a metal ion selected from the group consisting of a stable isotope of the lanthanides, tantalum, bismuth or other element with a molecular weight higher than iodine, and a tetraazacyclo compound, the complex being charge neutral in aqueous solution.
Dependencies are inferred from the claim text.