PVA hydrogel, hydrogel laminate using the same and hydrogel wound-dressing material using the same
AssigneesNichiban Co., Ltd., Japan Atomic Energy Research Institute
InventorsKeizo Makuuchi, Fumio Yoshii, Yasuaki Kitazaki, Kotohiko Shinozaki, Kazuki Isobe, Yuko Nishisako
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Abstract
Disclosed are a PVA hydrogel which comprises being obtained by irradiating a polyvinyl alcohol aqueous solution containing a polymer selected from the group consisting of polyvinyl pyrrolidone, a methyl vinyl ether-maleic anhydride copolymer and an isobutylene-maleic anhydride copolymer, with ionizing radiations, a process for preparing the PVA hydrogel, a hydrogel laminate using the PVA hydrogel, a process for preparing the hydrogel laminate, and a hydrogel wound-dressing material using the PVA hydrogel.
Claims25
A process for preparing a hydrogel laminate, which comprises:
- coating a polyvinyl alcohol aqueous solution, said solution optionally comprises at least one polymer selected from the group consisting of polyvinyl pyrrolidone, a methyl vinyl ether-maleic anhydride copolymer and an isobutylene-maleic anhydride copolymer, to form at least one hydrogel layer, on a previously formed polyvinyl alcohol hydrogel layer, followed by irradiating the polyvinyl alcohol aqueous solution with ionizing radiation.
A process for preparing a hydrogel laminate, which consists essentially of:
- (a) coating a layer of a polyvinyl alcohol aqueous solution on a previously formed polyvinyl alcohol hydrogel layer, said polyvinyl alcohol aqueous solution optionally comprises at least one polymer selected from the group consisting of polyvinyl pyrrolidone, a methyl vinyl ether-maleic anhydride copolymer and an isobutylene-maleic anhydride copolymer,
- (b) thereafter irradiating said polyvinyl alcohol aqueous solution with ionizing radiation, said layer of said polyvinyl alcohol aqueous solution having a thickness which is adjusted depending on the permeating ability of said ionizing radiation to crosslink said polyvinyl alcohol aqueous solution, to form said at least one hydrogel layer of said polyvinyl alcohol aqueous solution on said previously formed polyvinyl alcohol hydrogel layer.
Dependencies are inferred from the claim text.