Compensating for magnetization transfer effects in multislice and three-dimensional MRI blood flow mapping studies
AssigneeBeth Israel Deaconess Medical Center, Inc.
InventorRobert R. Edelman
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Abstract
To compensate for magnetization transfer effects that result from use of a labeling pulse to label inflowing blood, at least two control pulses are used. The control pulses have a total compensating flip angle that equals the flip angle of the labeling pulse, and are applied to the same volume to which the labeling pulse is applied. Advantageously, the labeling and control pulses are adiabatic.
Claims13
A method for compensating for magnetization transfer effects, comprising the following steps:
- applying a labeling pulse having a predetermined flip angle to a predetermined volume of interest;
- and
- applying at least two control pulses to said predetermined volume of interest, said at least two control pulses having a total compensating flip angle equal to said predetermined flip angle.
A method of conducting a multislice MRI blood flow mapping study within a volume of interest using in such a manner as to compensate for magnetization transfer effects, comprising the following steps:
- using a labeling pulse to label blood within a predetermined volume that is arterially upstream of the volume of interest, said labeling pulse having a predetermined flip angle;
- acquiring labeled-blood MR data from the volume of interest using an MR pulse sequence;
- applying at least two control pulses to said predetermined volume, said at least two control pulses having a total compensating flip angle equal to said predetermined flip angle;
- and
- acquiring compensated-blood MR data from the volume of interest using the MR pulse sequence.
Dependencies are inferred from the claim text.