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US 5,845,640 AGranted
Chemiluminescent sources for photodynamic therapy and photomedicine
AssigneeSpectra Science Corporation
InventorNabil M. Lawandy
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AssigneeSpectra Science Corporation
InventorNabil M. Lawandy
Estimating the term…
An optical source (10) for exciting a photosensitive drug that responds to light within a predetermined band of wavelengths. The optical source uses a chemiluminescent source in combination with at least one fluorescer selected to output light within the predetermined band of wavelengths. The chemiluminescent source can be flowed during use. In one embodiment the chemiluminescent source is stored in a heated reservoir, and is pumped from the reservoir through a conduit, such as a catheter. A patch can be used for spreading the chemiluminescent source over a wider area. An active feedback system can also be used for controlling the output light. In preferred embodiments a plurality of reactants are mixed for forming a chemiluminescent source in combination with at least one fluorescer selected to output light within the predetermined band of wavelengths. The mixing of the reactants causes an excitation of the at least one selected fluorescer by energy transfer from an energetic immediate in a chemiluminescent reaction to provide a fluorescent emission in the predetermined band of wavelengths.
An optical source for exciting a photosensitive drug that responds to light within a predetermined band of wavelengths, comprising a chemiluminescent source in combination with at least one fluorescer selected to output light within the predetermined band of wavelengths;
An optical source for exciting a photosensitive drug that responds to light within a predetermined band of wavelengths, comprising a chemiluminescent source in combination with at least one fluorescer selected to output light within the predetermined band of wavelengths;
A catheter for insertion into a body cavity, said catheter having at least one region that is transparent to light having wavelengths within a predetermined band of wavelengths selected for exciting a photosensitive drug, said catheter comprising a conduit for flowing a chemiluminescent source in combination with at least one fluorescer selected to output light within the predetermined band of wavelengths.
A patch for application to a surface of a tissue, said patch having at least one region that is transparent to light having wavelengths within a predetermined band of wavelengths selected for exciting a photosensitive drug, said patch comprising an internal chamber region for flowing therethrough a chemiluminescent source in combination with at least one fluorescer selected to output light within the predetermined band of wavelengths.
A patch for application to a surface of a tissue, said patch having at least one region that is transparent to light having wavelengths within a predetermined band of wavelengths selected for exciting a photosensitive drug, said patch having at least one region that is transparent to light having wavelengths within a predetermined band of wavelengths selected for exciting a photosensitive drug, said patch comprising a plurality of compartments, individual ones of said compartments containing one of a plurality of reactants;
A method for generating light having wavelengths within a predetermined band of wavelengths selected for exciting a photosensitive drug, comprising steps of:
A source of light having wavelengths within a predetermined band of wavelengths selected for exciting a photosensitive drug, comprising:
Dependencies are inferred from the claim text.