Method and device for delivering fibrin glue
AssigneeBayer Aktiengesellschaft
InventorsThomas P. Zimmerman, Christopher A. Dadd, George A. Baumbach
Life of this patent
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Abstract
A method and device for activating and applying a solution of fibrinogen to a desired site. The method includes contacting the solution of fibrinogen with immobilized thrombin resulting in an activated solution of polymerizable fibrin, and delivering the activated solution to the desired site. The device includes a housing having a compartment for a solution of fibrinogen, immobilized thrombin, a structure for bringing the solution of fibrinogen in contact with the immobilized thrombin under conditions which permit the activation of the fibrinogen resulting in polymerizable fibrin, and a structure for delivery of the activated solution to the desired site.
Claims9
A device for applying an activated solution of polymerizable fibrin from an exit port to a desired site, the device comprising:
- a) a syringe-like device having a barrel, the barrel having a compartment for a solution of fibrinogen and a tip connected to the compartment,
- b) a cartridge having an entrance port, the exit port, and an intermediate housing, the housing defining an interior space confluent with the entrance port and the exit port, the entrance port being affixable to the tip of the barrel, and
- c) a water-insoluble support having thrombin immobilized upon the support, the support being contained within the interior space of the cartridge housing.
A device comprising a cartridge having an entrance port, an exit port, and an intermediate housing, the housing defining an interior space confluent with the entrance port and the exit port, the entrance port being affixable to a syringe-like device, the device further comprising biologically active thrombin immobilized on a water-insoluble support, the support being contained within the interior space of the cartridge housing.
Dependencies are inferred from the claim text.