Human acute phase response factor
AssigneeTadamitsu Kishimoto
InventorsTadamitsu Kishimoto, Shizuo Akira
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Abstract
Mammal transcription factor APRF, process for the preparation of it, DNAs encoding the product, replication and expression vector comprising the DNA, host cells transformed or tranfected with the replication and expression vector, evaluating and screening method for searching an inhibitory agent on the function of APRF and an inhibitory agent against the function of the APRF. The peptide of the present invention (APRF) may be useful for complement or suppression of the function of APRF, screening an inhibitory agent against the function of APRF. Inhibiting agent containing the product as active ingredient of the present invention may be also useful for treatment of diseases related to cytokine such as IL-6, i.e. inflammatory diseases.
Claims2
An isolated human APRF polypeptide comprising the amino acid sequence of SEQ ID NO:1.
Dependencies are inferred from the claim text.