Loading patent…
AssigneeThe United States of America as represeneted by the Department of Health and Human Services
InventorDvorit Samid
Estimating the term…
Compositions and methods of treating anemia, cancer, AIDS, or severe .beta.-chain hemoglobinopathies by administering a therapeutically effective amount of phenylacetate or pharmaceutically acceptable derivatives thereof or derivatives thereof alone or in combination or in conjunction with other therapeutic agents including retinoids, hydroxyurea, and flavonoids. Intravesicle methods of treatment of cancers phenylacetate. Pharmacologically-acceptable salts alone or in combinations and methods of preventing AIDS and malignant conditions, and inducing cell differentiation are also aspects of this invention. A product as a combined preparation of phenylacetate and a retinoid, hydroxyurea, or flavonid (or other mevalonate pathway inhibitor) for simultaneous, separate, or sequential use in treating a neoplastic condition in a subject. Methods of modulating lipid metabolism and/or reducing serum triglycerides in a subject using phenylacetate.
A method of sensitizing a subject to radiation therapy or chemotherapy, comprising administering a therapeutic amount of a compound of the formula:
A method of treating a neoplastic condition in a subject resistant to radiation and chemotherapy, comprising administering to the subject a therepeutic amount of a phenylacetic acid derivative of the formula:
A method of sensitizing a subject to radiation therapy or chemotherapy, wherein the subject has a neoplastic condition resistant to radiation or chemotherapy, comprising administering to the subject a therapeutic amount of a compound of the formula:
A method of treating a neoplastic condition in a subject comprising the steps of:
Dependencies are inferred from the claim text.