Methods of inhibiting melanoma using Benzothiophenes as cytotoxic agents per se
AssigneeEli Lilly and Company
InventorRobert A. Swift
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Abstract
A method of inhibiting melanoma comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR1## wherein R.sup.1 and R.sup.3 are independently hydrogen, ##STR2## wherein Ar is optionally substituted phenyl; R.sup.2 is selected from the group consisting of pyrrolidine, hexamethyleneamino, and piperidino, or a pharmaceutically acceptable salt of solvate thereof; alone or in combination with one or more melanoma-inhibiting agents.
Claims5
A method of inhibiting melanoma comprising administering to a human in need thereof an effective amount of a compound having the formula ##STR5## wherein R.sup.1 and R.sup.3 are independently hydrogen, ##STR6## wherein Ar is optionally substituted phenyl;
- R.sup.2 is selected from the group consisting of pyrrolidine, hexamethyleneimino, and piperidino;
- or a pharmaceutically acceptable salt of solvate thereof;
- as a cytotoxic agent per se, alone or in combination with one or more melanoma-inhibiting agents.
Dependencies are inferred from the claim text.