Method and composition for treating erectile dysfunction
OwnerNils G. Kock, Gerhard Lyckeinventors
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Abstract
Lipophilic active substance composition and its use in a new method of treating erectile dysfunction by administration thereof, optionally together with a hydrophilic vehicle and optionally an antibacterial agent into the urethra.
Claims27
A pharmaceutical composition for administration to the urethra of a male individual to produce penile erection, comprising an effective amount of a lipophilic active agent dispersed in a hydrophilic vehicle, wherein;
- (a) the hydrophilic vehicle is suitable for urethral administration and effective to facilitate passage of the lipophilic active agent through the urethral membrane so that the active agent reaches the corpora cavernosa;
- and
- (b) the lipophilic active agent comprises an .alpha..sub.1 -receptor blocking agent present in the composition at a concentration effective to produce penile erection following administration of the composition to the urethra of the male individual.
A method for treating erectile dysfunction in a male individual, comprising administering to the urethra of the individual an effective amount of a pharmaceutical composition comprising a known and therapeutically effective dosage of a lipophilic active agent selected from the group consisting of .alpha..sub.1 -receptor blockers and combinations thereof, and a hydrophilic vehicle suitable for urethral administration and effective to facilitate passage of the lipophilic active agent through the urethral membrane so that the active agent reaches the corpora cavernosa and produces penile erection.
Dependencies are inferred from the claim text.