US 5,843,918 AGranted

Anti-endotoxin compounds

AssigneeEisai Co., Ltd.

InventorsWilliam J. Christ, Lynn D. Hawkins, Tsutomu Kawata, Daniel P. Rossignol, Seiichi Kobayashi, Osamu Asano

Life of this patent

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Abstract

Disclosed are lipid A analogs useful for the treatment of septic shock and LPS-mediated activation of viral infection.

Claims1

Dependent claims

A method for treating sepsis in a mammal, said method comprising administering to said mammal a therapeutic composition containing a compound having the formula:

##STR290## or a pharmaceutically-acceptable salt thereof.

Dependencies are inferred from the claim text.

Facts

Application: 08/472,820Filed 7 Jun 1995 · division
Priority: 11 Oct 1991
Granted: 1 Dec 1998
Term ends: Not estimatedThe source records don’t support an estimate.

Classification7 codes

C07H 13/06
Having the esterifying carboxyl radicals attached to acyclic carbon atoms: fatty acids
A61P 31/04
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics: antibacterial agents
A61P 31/12
Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics: antivirals
A61P 31/18
For RNA viruses: for HIV

Family

Serial776,100Parent of this continuation-in-part · filed 11 Oct 1991
Serial935,050Parent of this division · filed 25 Aug 1992
US 5,530,113 AParent of this division
US 5,843,918 AThis patent

From the US filing history. Foreign family members aren’t listed.

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