Pharmaceutical acceptable compositions containing an alcohol and a hydrophobic drug
OwnerBernard C. Shermaninventor
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Abstract
Pharmaceutical compositions having improved physical and absorption properties are disclosed, wherein a hydrophobic drug is dissolved in a solvent system comprising at least one alcohol having a boiling point above 100.degree. C. and a solubility in water inferior to 10 g per 100 g at 20.degree. C. and a surfactant.
Claims17
A water-dispersible pharmaceutical composition comprising a monocyclic non-polar peptide dissolved in a solvent system, wherein the solvent system comprises at least one alcohol selected from saturated alkyl mono-alcohols having from 6 to 16 carbon atoms per molecule, a boiling point above 100.degree. C. and a solubility in water of less than 10 g per 100 g at 20.degree. C., and said solvent system further comprises at least one pharmaceutically-acceptable surfactant.
Dependencies are inferred from the claim text.